Fitness costs of individual and combined pyrethroid resistance mechanisms, kdr and CYP-mediated detoxification, in Aedes aegypti.
BackgroundAedes aegypti is an important vector of many human diseases and a serious threat Toy Ponies to human health due to its wide geographic distribution and preference for human hosts.A.aegypti also has evolved widespread resistance to pyrethroids due to the extensive use of this insecticide class over the past decades.Mutations that cause ins